Face-Off: Penguins 2009 Regular Season Schedule
| Opponent | Date | Time** | Location |
| N.Y. Rangers | 10/2/09 | 7:30 p.m. | Home |
| N.Y. Islanders | 10/3/09 | 7 p.m. | Away |
| Phoenix | 10/7/09 | 7:30 p.m. | Home |
| Philadelphia | 10/8/09 | 7 p.m. | Away |
| Toronto | 10/10/09 | 7 p.m. | Away |
| Ottawa | 10/12/09 | 7:30 p.m. | Away |
| Carolina | 10/14/09 | 7 p.m. | Away |
| Tampa Bay | 10/17/09 | 7:30 p.m. | Home |
| St. Louis | 10/20/09 | 7 p.m. | Home |
| Florida | 10/23/09 | 7:30 p.m. | Home |
| New Jersey | 10/24/09 | 7:30 p.m. | Home |
| Montreal | 10/28/09 | 7:30 p.m. | Home |
| Columbus | 10/30/09 | 7 p.m. | Away |
| Minnesota | 10/31/09 | 7:30 p.m. | Home |
| Anaheim | 11/3/09 | 10 p.m. | Away |
| Los Angeles | 11/5/09 | 10:30 p.m. | Away |
| San Jose | 11/7/09 | 10:30 p.m. | Away |
| Boston | 11/10/09 | 7 p.m. | Away |
| New Jersey | 11/12/09 | 7:30 p.m. | Home |
| Boston | 11/14/09 | 7:30 p.m. | Home |
| Anaheim | 11/16/09 | 7:30 p.m. | Home |
| Ottawa | 11/19/09 | 7:30 p.m. | Away |
| Atlanta | 11/21/09 | 7 p.m. | Away |
| Florida | 11/23/09 | 7:30 p.m. | Away |
| Montreal | 11/25/09 | 7:30 p.m. | Home |
| N.Y. Islanders | 11/27/09 | 2 p.m. | Away |
| N.Y. Rangers | 11/28/09 | 7:30 p.m. | Home |
| N.Y. Rangers | 11/30/09 | 7 p.m. | Away |
| Colorado | 12/3/09 | 7:30 p.m. | Home |
| Chicago | 12/5/09 | 7:30 p.m. | Home |
| Carolina | 12/7/09 | 7:30 p.m. | Home |
| Montreal | 12/10/09 | 7:30 p.m. | Away |
| Florida | 12/12/09 | 7:30 p.m. | Home |
| Philadelphia | 12/15/09 | 7 p.m. | Home |
| Philadelphia | 12/17/09 | 7 p.m. | Away |
| Buffalo | 12/19/09 | 7 p.m. | Away |
| New Jersey | 12/21/09 | 7:30 p.m. | Home |
| Ottawa | 12/23/09 | 7 p.m. | Home |
| Toronto | 12/27/09 | 7 p.m. | Home |
| Buffalo | 12/29/09 | 7 p.m. | Away |
| New Jersey | 12/30/09 | 7 p.m. | Away |
| Tampa Bay | 1/2/10 | 3 p.m. | Away |
| Florida | 1/3/10 | 5 p.m. | Away |
| Atlanta | 1/5/10 | 7:30 p.m. | Home |
| Philadelphia | 1/7/10 | 7:30 p.m. | Home |
| Toronto | 1/9/10 | 7 p.m. | Away |
| Minnesota | 1/11/10 | 8 p.m. | Away |
| Calgary | 1/13/10 | 9:30 p.m. | Away |
| Edmonton | 1/14/10 | 9:30 p.m. | Away |
| Vancouver | 1/16/10 | 10 p.m. | Away |
| N.Y. Islanders | 1/19/10 | 7:30 p.m. | Home |
| Washington | 1/21/10 | 7:30 p.m | Home |
| Philadelphia | 1/24/10 | 3 p.m. | Away |
| N.Y. Rangers | 1/25/10 | 7 p.m. | Away |
| Ottawa | 1/28/10 | 7 p.m. | Home |
| Detroit | 1/31/10 | 3 p.m. | Home |
| Buffalo | 2/1/10 | 7 p.m. | Home |
| Montreal | 2/6/10 | 3 p.m. | Away |
| Washington | 2/7/10 | 3 p.m. | Away |
| N.Y. Islanders | 2/10/10 | 7:30 p.m. | Home |
| N.Y. Rangers | 2/12/10 | 7:30 p.m. | Home |
| Nashville | 2/14/10 | 1 p.m. | Home |
| Buffalo | 3/2/10 | 7:30 p.m. | Home |
| N.Y. Rangers | 3/4/10 | 7 p.m. | Away |
| Dallas | 3/6/10 | 1 p.m. | Home |
| Boston | 3/7/10 | 3 p.m. | Home |
| Carolina | 3/11/10 | 7 p.m. | Away |
| New Jersey | 3/12/10 | 7 p.m. | Away |
| Tampa Bay | 3/14/10 | 5 p.m. | Away |
| New Jersey | 3/17/10 | 7 p.m. | Away |
| Boston | 3/18/10 | 7 p.m. | Away |
| Carolina | 3/20/10 | 1 p.m. | Home |
| Detroit | 3/22/10 | 7 p.m. | Away |
| Washington | 3/24/10 | 7 p.m. | Away |
| Philadelphia | 3/27/10 | 1 p.m. | Home |
| Toronto | 3/28/10 | 5 p.m. | Home |
| Tampa Bay | 3/31/10 | 7:30 p.m. | Home |
| Atlanta | 4/3/10 | 1 p.m. | Home |
| Washington | 4/6/10 | 7 p.m. | Home |
| N.Y. Islanders | 4/8/10 | 7:30 p.m. | Home |
| Atlanta | 4/10/10 | 7 p.m. | Away |
| N.Y. Islanders | 4/11/10 | 5 p.m. | Away |
